Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Air Europa

The cheapest airline(s) flying from Madrid to Panama City is Air Europa.

  • Air Europa Air Europa
  • Air France Air France
  • KLM KLM
  • Iberia Iberia
  • Avianca Avianca
  • American Airlines American Airlines
  • Turkish Airlines Turkish Airlines
  • United Airlines United Airlines
Cheapest Month March

Travel Period: February 2025 - January 2026

The cheapest month(s) to fly from Madrid to Panama City is March.

  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
Cheapest Day of the Week Tuesday

The cheapest day(s) of the week to fly from Madrid to Panama City is Tuesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Thu, 2 Jan, 2025

  • Time Earliest
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    • Earliest
    • Latest
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  • Availability
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  • 06:00 MAD
    16:25 PTY
    16Hrs, 25m 1 Stop (AMS)
  • MADMadrid Barajas Airport 06:00 - PTY 16:25 16h 25m 1 Stop (AMS) Amsterdam
  • MADMadrid Barajas Airport 06:00
    AMSAmsterdam Airport 11:20
  • AMSAmsterdam Airport 08:40
    PTYPanama City Tocumen International Airport 16:25
  • 16h 25m (2h 40m)
  • 1 Stop AMS · Amsterdam 2h 40m
  • KLM (KL 1500)Boeing 737 800
    KLM (KL 757)Boeing Dreamliner Series 10
  • KLM (KL 1500)
    • M
    • T
    • W
    • T
    • F
    • S
    • S
  • 18:00 MDE
    12:55 BOG
    16Hrs, 45m 1 Stop (PTY)
  • MDEMedellin Jose Maria Cordova Intl Airport 18:00 - BOG 12:55 16h 45m 1 Stop (PTY) Panama City
  • MDEMedellin Jose Maria Cordova Intl Airport 18:00
    MADMadrid Barajas Airport 08:30
  • PTYPanama City Tocumen International Airport 19:15
    BOGBogota Airport 12:55
  • 16h 45m (4h 04m)
  • 1 Stop PTY · Panama City 4h 04m
  • Avianca (AV 316)Airbus
    Avianca (AV 27)Boeing 787 8
  • Avianca (AV 316)
    • M
    • T
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    • T
    • F
    • S
    • S
  • 08:30 MAD
    21:00 PTY
    18Hrs, 30m 1 Stop (BOG)
  • MADMadrid Barajas Airport 08:30 - PTY 21:00 18h 30m 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 08:30
    BOGBogota Airport 19:15
  • BOGBogota Airport 12:55
    PTYPanama City Tocumen International Airport 21:00
  • 18h 30m (6h 20m)
  • 1 Stop BOG · Bogota 6h 20m
  • Avianca (AV 27)Boeing 787 8
    Avianca (AV 56)Airbus
  • Avianca (AV 27)
    • M
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    • T
    • F
    • S
    • S
  • 08:30 MAD
    16:30 PTY
    14Hrs, 00m 1 Stop (BOG)
  • MADMadrid Barajas Airport 08:30 - PTY 16:30 14h 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 08:30
    BOGBogota Airport 14:35
  • BOGBogota Airport 12:55
    PTYPanama City Tocumen International Airport 16:30
  • 14h (1h 40m)
  • 1 Stop BOG · Bogota 1h 40m
  • Avianca (AV 27)Boeing 787 8
    Avianca (AV 60)Airbus
  • Avianca (AV 27)
    • M
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    • T
    • F
    • S
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  • 10:55 MAD
    21:00 PTY
    16Hrs, 05m 1 Stop (BOG)
  • MADMadrid Barajas Airport 10:55 - PTY 21:00 16h 05m 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 10:55
    BOGBogota Airport 19:15
  • BOGBogota Airport 15:20
    PTYPanama City Tocumen International Airport 21:00
  • 16h 05m (3h 55m)
  • 1 Stop BOG · Bogota 3h 55m
  • Avianca (AV 183)Boeing 787 8
    Avianca (AV 56)Airbus
  • Avianca (AV 183)
    • M
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    • T
    • F
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  • 16:20 MAD
    00:20 PTY
    14Hrs, 00m 1 Stop (BOG)
  • MADMadrid Barajas Airport 16:20 - PTY 00:20 14h 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 16:20
    BOGBogota Airport 22:30
  • BOGBogota Airport 20:50
    PTYPanama City Tocumen International Airport 00:20
  • 14h (1h 40m)
  • 1 Stop BOG · Bogota 1h 40m
  • Avianca (AV 11)Boeing 787 8
    Avianca (AV 40)Airbus
  • Avianca (AV 11)
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  • 16:20 MAD
    01:00 PTY
    14Hrs, 40m 1 Stop (BOG)
  • MADMadrid Barajas Airport 16:20 - PTY 01:00 14h 40m 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 16:20
    BOGBogota Airport 23:10
  • BOGBogota Airport 20:50
    PTYPanama City Tocumen International Airport 01:00
  • 14h 40m (2h 20m)
  • 1 Stop BOG · Bogota 2h 20m
  • Avianca (AV 11)Boeing 787 8
    Avianca (AV 40)Airbus
  • Avianca (AV 11)
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  • 00:35 MAD
    09:40 PTY
    15Hrs, 05m 1 Stop (BOG)
  • MADMadrid Barajas Airport 00:35 - PTY 09:40 15h 05m 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 00:35
    BOGBogota Airport 07:50
  • BOGBogota Airport 05:00
    PTYPanama City Tocumen International Airport 09:40
  • 15h 05m (2h 50m)
  • 1 Stop BOG · Bogota 2h 50m
  • Avianca (AV 47)Boeing 787 8
    Avianca (AV 8380)Airbus
  • Avianca (AV 47)
    • M
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    • -
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  • 00:35 MAD
    09:40 PTY
    15Hrs, 05m 1 Stop (BOG)
  • MADMadrid Barajas Airport 00:35 - PTY 09:40 15h 05m 1 Stop (BOG) Bogota
  • MADMadrid Barajas Airport 00:35
    BOGBogota Airport 07:50
  • BOGBogota Airport 05:00
    PTYPanama City Tocumen International Airport 09:40
  • 15h 05m (2h 50m)
  • 1 Stop BOG · Bogota 2h 50m
  • Avianca (AV 47)Boeing 787 8
    Avianca (AV 58)Airbus A320 Neo
  • Avianca (AV 47)
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What’s the most popular airline flying from Madrid to Panama City?

The most popular airline flying from Madrid to Panama City is Air Europa. Find the latest flight deals on Wego.

How far is Panama City from Madrid?

The flight distance between Madrid and Panama City is 8163km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 00:35. The last flight of the day departs at 06:00. See the full list of flight times on Wego.